ARPA-H Dash Update!

Hi Guys!

We would like to thank all of you who voted for us in the ARPA-H Dash competition! We are very happy to have made it into the Final 4. While out of the 484 proposals, we didn’t progress to the Finals, we are extremely happy to have made to the Final 4!!

ARPA-H (The Advanced Research Projects Agency for Health), proposed by President Biden, was created to improve the U.S. government’s ability to speed biomedical and health research.

By making it this far, we will now have an opportunity for follow-up technical workshops with ARPA-H Program Managers to further vet and build out our idea – Mental Health Moonshot! – for potential future research and development. This is a huge step for mental health research!

Thank you all again!

Please Vote!


I have an urgent request for moving mental health research forward. Cure Brain Disease has submitted a proposal to “ARPA-H Dash to Accelerate Health Outcomes” which is an online competition to identify revolutionary ideas to transform health. We have made it to the third round of the judging competition, and have entered into the fourth round. This is the public voting round, and we really need your vote!

The round closes on this Thursday, May 4th, so please vote.

Here is the link to register to sign up so you can place your vote.

There are 4 focus areas, and we are in “Resilient Systems”. The title of our proposal is “Mental Health Moonshot!” You’ll need to click on VOTE in the upper center of the screen, and scroll through by clicking ‘Skip’ for each head to head pairing until you come to our pairing entry. Please click ‘Select’ for Mental Health Moonshot!, and then make sure to click, ‘Vote’. We’d love it if you go to our page and click Good Evidence.

If you would, please share with anyone you would like. So you’ll know before going on, I’ve included a copy of our proposal. (below)



Title: Mental Health Moonshot!

Proposed Health Transformation:We propose serious mental disorders be researched and treated as individually distinct diseases utilizing genetic/epigenetic studies with the goal of developing novel, targeted treatments and cures.

Current Implementation:Current treatments rely heavily on subjective feedback and outdated medications to hopefully manage symptoms. This leaves no prospect of finding cures based on the molecular causes of brain disorders

What’s New: Serious mental disorders share common genetic roots, yet each disorder presents differently per individual. Aim – Identify biomarkers of shared disorder populations, followed by epigenetic studies.

Evidence Statement: Major mental disorders such as schizophrenia bipolar disorder and major depressive disorder share common genetic roots but each disorder presents differently in each individual.

Evidence Citation: Distinctness of mental disorders traced to differences in gene readouts individual%2C%E2%80%9D%20said%20Francis%20J.